What are the causes of pyometra in dogs? What are the dangers of pyometra in dogs?

Causes of pyometra in dogs
1. Endometrial hyperplasia. A female dog with a normal estrus cycle will be in estrus for two weeks. At this time, the ovaries will secrete progesterone. The endometrium will be stimulated by repeated exposure to high concentrations of estrogen and progesterone. If she has not become pregnant, During the operation, the endometrium will proliferate. 2. The endometrium of common Escherichia coli will secrete a lot of nutrients (highly nutritious substances. In order to get pregnant, the endometrium secretes a lot of nutrients to assist the implantation of the fertilized embryo and provide a basic source of nutrients). At this time, if the animal When in proestrus or estrus, the cervix will open slightly, so vaginal bacteria can easily pass through the cervix and enter the uterus to multiply. The most common bacteria is E. coli. 3. Bacterial infection Pyometra is a phenomenon in which the cyst-like structures of the endometrium are infected by bacteria and produce a large amount of secretions. After the sick dog was seriously infected by bacteria, it triggered a series of physiological reactions. 4. Impact of bacterial toxins The toxins in the bacteria will further affect the operation of the heart, reduce the blood perfusion of the kidneys, and then lead to uremia. In severe cases, it will cause multiple organ failure and death of sick dogs. Premonitory symptoms of pyometra in dogs
Pyometra is the most common gynecological disease among female dog diseases. It refers to the accumulation of a large amount of pus in the uterine cavity of dogs, accompanied by endometrium abnormalities. Hyperplasia and bacterial infection can be divided into closed type and open type according to whether the cervix is open or not.1. Common symptoms
It usually occurs 38 weeks after estrus. At first, there is fever, depression, decreased appetite, reduced activity, lethargy, and sometimes vomiting. As the disease progresses, the appetite gradually disappears and the desire to drink gradually increases. Affected dogs become emaciated, have an enlarged abdominal circumference, and suffer from physical failure.2. Closed pyometra
Accounting for 59.6% of the statistical cases 28/47 The cervix is completely blocked, no purulent secretions are discharged from the vulva, the abdominal circumference is large, breathing and heartbeat are impaired Accelerates, and in severe cases, it is difficult to breathe, the abdominal skin is tense, the subcutaneous veins in the abdomen are distended, and the patient likes to lie down.3. Open pyometra
This type of cases accounts for 40.4% of 19/47 cases. The cervical canal is not completely closed, and a small amount of purulent secretion flows out from the vulva from time to time. It is cheese-colored, Gray or reddish-brown, with an unpleasant odor, often contaminating the vulva, tail root and hocks. The affected dog's vulva is red and swollen, the vaginal mucosa is flushed, and the abdominal circumference is slightly enlarged.How to treat pyometra
1. The radical cure for pyometra is to surgically remove the ovaries and uterus. For cases where the owner is unwilling to undergo surgery or whose physical condition does not allow for surgery, drug treatment combined with uterine flushing can also be used to cure the disease, but this method is prone to recurrence.2. Pyometra will not occur after sterilization or after giving birth to one child.
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