What should I do if my dog ​​has "systemic lupus erythematosus"? What should I do if my dog ​​suffers from lupus erythematosus?

Jul 26,2025
3Min

Causes of systemic lupus erythematosus in dogs:

As in humans, the exact cause of systemic lupus erythematosus in dogs is still unknown to science. It can only be roughly determined to be an immune disease.

Clinical symptoms of systemic lupus erythematosus in dogs:

1. The main symptoms in dogs are: fever, polyarthritis, thrombocytopenia, erythematous ulcers on the skin and mucous membranes, edema, hematuria, difficulty chewing, and swollen lymph nodes. Large, systemic lupus erythematosus (LE) cells. 2. The most important cause of the appearance of systemic lupus erythematosus (LE) cells in dogs is damage to muscles and joints. 3. Muscle weakness, stiffness, joint swelling, lameness and limb edema related to intermittent fever are the most common clinical symptoms. 4. In terms of medical history, it is generally seen that the quiescent and active phases of the disease appear alternately. At this time, the dog can be given an appropriate dose of corticosteroids; later giving a smaller maintenance dose can generally reduce the severe impact of autoimmune diseases.

Prevention and treatment measures for canine systemic lupus erythematosus:

1. Immunosuppressive therapy: Prednisone 1.5~3.0 mg/kg body weight, taken orally once every morning, halved for 10 days, and the next day after 1 month Oral maintenance dose: cyclophosphamide or Imulan 2 mg/kg body weight, once a day, stop taking the medicine after 4 days, then start again after 3 days, stop taking the medicine when the white blood cells reduce to 5000/cubic millimeter. 2. When thrombocytopenia and thrombocytopenic purpura occur, vincristine 0.2 mg/kg body weight can be injected intravenously every week. 3. When the above methods fail to treat hemolytic anemia and thrombocytopenic purpura, the dog’s spleen can be surgically removed. 4. Food therapy: You can choose dog food and prescription food that are free of systemic allergic reactions.

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