The effect of gentamicin on dogs

Nov 10,2023
3Min
What is the role of dogs taking gentamicin? Many times dogs take gentamicin to stop diarrhea; however, there are many reasons for dogs to have diarrhea. You must not feed gentamicin regardless of the reason. Gentamicin is an antibiotic that will destroy the balance of gastrointestinal flora and affect normal digestion and absorption.

Dog diarrhea can be caused by many reasons. You must not feed Qingda regardless of the reason. The problem that can be solved by two lactase pills, but using Qingda will destroy the balance of gastrointestinal flora. , affecting normal digestion and absorption. In addition, this drug has certain toxicity to the kidneys and auditory nerves, and overdose is even more harmful.

Gentamicin sulfate (gentamicin sulfate)

【Function and use】

This product is an aminoglycoside broad-spectrum antibiotic that has bacteriostatic and bactericidal effects on a variety of Gram-negative and Gram-positive bacteria. It has a strong effect on Gram-negative bacteria such as Pseudomonas aeruginosa, Aerobacillus aerogenes, Pneumoniae, Salmonella, Escherichia coli, Proteus and Staphylococcus aureus.

The mechanism of action of this product is to firmly bind to specific proteins on the subunits of bacterial ribosomes, interfere with ribosome functions, prevent protein synthesis, and cause errors in the code on the translated messenger ribonucleic acid (mRNA), leading to ineffective synthesis. Functional proteins.

Clinically used for sepsis, respiratory tract infection, biliary tract infection, purulent peritonitis, and intracranial infection caused by Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, Shigella dysenteriae, Klebsiella, Proteus and other sensitive bacteria. , urinary tract infection and dysentery and other diseases.

【Side effects】

1. Similar to kanamycin, it has a greater impact on the vestibule of the ear, but less damage to the cochlea. The main manifestations are dizziness, vertigo and tinnitus. For children with renal insufficiency or children, more attention should be paid to toxic reactions, which may lead to hearing loss or even deafness in severe cases.

2 Since this product has a blocking effect on neuromuscular junctions, it is not suitable for intravenous injection or large-dose rapid intravenous infusion to prevent the occurrence of respiratory depression.

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