What should you pay attention to when vaccinating your dog? Immunization matters you don’t know

Jul 26,2025
8Min

Overview of all types of domestic vaccines

Currently, domestic small animal clinical vaccines are divided into two categories: domestically produced and imported vaccines. Among domestic vaccines, only a few brands of vaccines are regular products that have been tested and approved by the relevant veterinary and veterinary drug departments. Among them, the "Best" canine pentavalent vaccine developed by researchers Xia Xianzhu of the Military Supplies University and others has received better feedback from users. Domestic dog vaccines include seven-combination vaccine, five-combination vaccine and single vaccine.

The quality of imported dog vaccines is better than domestic vaccines. Among them, the Dutch interway vaccine, the American Fortune vaccine and the American Pfizer vaccine are of good quality and have good clinical application results.

Imported vaccines are mainly six-linked vaccine and rabies vaccine. It mainly prevents canine distemper, canine parvovirus, leptospirosis, infectious hepatitis, bronchitis, parainfluenza, rabies, etc.

From many years of clinical observation in small animals, in terms of the protective power of dogs after vaccine injection, the clinical effect of the imported six-combination vaccine for dogs is better than that of the domestic five-combination vaccine.

The protective power of the domestically produced five-unit vaccine against canine parvovirus disease is no less than that of imported products, but the imported six-unit vaccine is more effective against canine distemper virus than the imported six-unit vaccine.

my country’s regulations on dog breeding require that dogs should be vaccinated against rabies. Vaccination against rabies is beneficial to both the dog and the health of the people who keep the dogs. It is worth noting that it is best to choose a single vaccine for rabies vaccination to ensure clinical effect.

Puppies can be vaccinated after they are 50 days old. If you choose to import the six-in-one vaccine, you can inoculate it 3 times in a row, with an interval of 4 weeks or 1 month between each time; if the puppy has reached 3 months of age (including adult dogs), you can inoculate it 2 times in a row, with an interval of 4 weeks or 1 month between each time. 1 month; thereafter, the imported six-link vaccine will be vaccinated once a year.

If you choose the domestically produced pentavalent vaccine, the vaccine should be injected three times continuously from the date of weaning (puppies are weaned on average 45 days), with an interval of 2 weeks each time; thereafter, the domestically produced pentavalent vaccine should be vaccinated once every six months.

Dogs over 3 months old should be vaccinated against rabies once a year.

Things you should pay attention to before vaccination for puppies

Puppies that have reached the vaccination age must have a physical examination before being vaccinated, because only healthy puppies can receive vaccinations.

Healthy means that the puppy is in a non-disease state, the puppy's nose is moist and cool, and the body temperature, breathing and heart function are normal. Clinical symptoms such as elevated body temperature, coughing, sneezing, vomiting, diarrhea, pus, urine, dry nose, thick foot pads, etc. should not occur; otherwise, in an unhealthy state, the puppies may be in the incubation period of infectious diseases, and vaccination will Cause disease.

When puppies are in new environments, such as riding in a car (especially in summer) or coming to a veterinary hospital with a complex smell, their body temperature will rise slightly due to stress. Under normal circumstances, the body temperature of puppies is about 38.5°C. Before coming to the animal hospital for vaccination, measure the dog's temperature at home and clamp the thermometer on the inside of the leg for 5 minutes to know the true temperature of the puppy.The real value can prevent the veterinarian from not agreeing to the vaccination after taking the car to the animal hospital because the body temperature exceeds 39.0°C.

Some experienced dog owners, who have experienced puppies dying from infectious diseases, first inject the puppies with canine five-part serum or canine two-part serum (canine distemper + canine parvovirus) after purchasing them. Antibodies) or canine distemper serum or canine parvovirus monoclonal antibodies. It is advisable to vaccinate puppies 3 weeks later. However, it should be noted that after injecting serum (antibodies), there should be an interval of about 20 days before vaccination ( antigen). Otherwise, if the interval is too short, it will cause antigen (vaccine) and antibody (serum) reactions, making the vaccine ineffective.

Reactions of dogs after vaccination

Under normal circumstances, dogs will not show major physical changes after vaccination. Some dogs will be reluctant to move and have poor appetite the day after vaccination. This is a temporary phenomenon and will return to normal soon. If the dog develops a rash or even becomes weak within 10 to 20 minutes after being vaccinated, it is an allergic reaction and a veterinarian should be consulted for immediate rescue.

Adverse reactions rarely occur when using the imported canine six-combination vaccine clinically. For safety reasons, 10 minutes after the puppy is vaccinated, the owner should stay in the animal hospital to observe the puppy's reaction, and then leave the animal hospital only if there is no abnormality.

Dog owners are reminded not to put their dogs on the ground when going to the animal hospital to vaccinate their puppies. It is best for the owner to hold the puppy or place it on a sterilized diagnostic table for physical examination to prevent contact infection.

If an infectious disease occurs about 7 days after the dog is vaccinated, it may be that the puppy was already in the incubation period of the infectious disease at the time of vaccination, or was infected with the disease during this period, and should receive corresponding treatment immediately.

Do not bathe the puppies within 1 week of vaccination to prevent respiratory diseases and immune failure.

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